Green tea extract and exercise may battle Alzheimer’s
A substance found in green tea, and exercise, may slow the progression of Alzheimer’s and reverse its effects, a new study on mice suggests.
MU professors accept the frequently found extract could lead to advancements in the treatment and prevention of Alzheimer’s disease in humans.
“Amyloid-beta peptide can gather in Alzheimer’s patients and clump together causing amyloid plaques in the brain,” said Todd Schachtman, professor of psychological sciences in the College of Arts and Science at MU.
“Symptoms can include dilemma, increased memory loss, restlessness and a lack of interest for your environment and surroundings.”
“We are searching for methods of avoiding or postponing the onset of the disease which we hope can eventually lead to an improvement of health status and quality of life for the elderly,” he said.
Scientists decided to search the effects of voluntary exercise and epigallocatechin-3-gallate (EGCG), a green tea extract, on memory function and A-beta levels in mice known to show plaque deposits and behaviour deficits.
First, mice were placed in the centre of a specialised maze and allowed to move around with the aim of finding the right gap.”
Schachtman along with his research team, including Jennifer Walker, a graduate student in psychology, and Agnes Simonyi, research associate professor in biochemistry, watched the mice to determine whether or not they could find the goal box, demonstrating memory and cognition.
In the second test, small “nestlets,” or squares containing materials to build nests, were placed in the terrain for different groups of mice. Next day, nests were scored based on shape and the amount of material used.